Daniel Boone

Fess Parker Daniel Boone

Ed Ames Mingo

Patricia Blair Rebecca Boone

Darby Hinton Israel Boone

Dal McKennon Cincinnatus

Veronica Cartwright Jemima Boone

Albert Salmi Yadkin

Ted White Aweetok (uncredited)

Orville Sherman Will Camfield

Harold Goodwin Loomis

Med Flory Joker

Jack Bannon Officer