Ultra City Smiths

Tom Waits The Narrator (voice)

Jimmi Simpson Detective David Mills (voice)

Da'Vine Joy Randolph Detective Gail Johnson (voice)

John C. Reilly Donovan Smith (voice)

Bebe Neuwirth Lady Andrea The Giant (voice)

Melissa Villaseñor Sister Mary Margaret (voice)

Kurtwood Smith Carpenter K. Smith (voice)

Tim Heidecker Mayor Kevin De Maximum (voice)

Chris Conrad Detective Nico Onasis (voice)

Julian Barratt The Most Dangerous Man in the World (voice)

Kristen Bell Donella Pecker (voice)

Luis Guzmán Rodrigo Smalls (voice)